Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535786 | 0.85 | SRD5A2 (0.42) | ALDH1A1GLAMTNR1AMTNR1BDHFR | |
| Acetic Acid SCHEMBL11383873 | 0.84 | MTNR1A (0.45) | ALDH1A1GLAMTNR1AMTNR1BDHFR | |
| SCHEMBL9539022 | 0.83 | ALDH1A1 (0.49) | ALDH1A1GLAMTNR1AMTNR1BDHFR | |
| SCHEMBL9588071 | 0.83 | ALDH1A1 (0.45) | ALDH1A1GLADHFRSMN1; SMN2KDM4E | |
| SCHEMBL11457360 | 0.81 | RHEB (0.51) | ALDH1A1GLAMTNR1AMTNR1BDHFR | |
| SCHEMBL6715526 | 0.81 | MTNR1A (0.60) | MTNR1AMTNR1BSMN1; SMN2KDM4ELMNA | |
| SCHEMBL11449730 | 0.80 | VDR (0.40) | ALDH1A1GLAMTNR1AMTNR1BDHFR | |
| SCHEMBL11449804 | 0.78 | ALDH1A1 (0.47) | ALDH1A1GLAMTNR1AMTNR1BDHFR | |
| SCHEMBL4891430 | 0.78 | ALDH1A1 (0.55) | ALDH1A1GLASMN1; SMN2LMNAMEN1 | |
| SCHEMBL4891437 | 0.78 | ALDH1A1 (0.55) | ALDH1A1GLASMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254595-A | Aryloxypropanolaminotetralins, a process for their preparation and pharmaceutical compositions containing them | ELF SANOFI (FR) | 1993-10-19 | — | — | US | disclosed |