Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ECE1 | P42892 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9588229 | 0.86 | LMNA (0.43) | LMNAALDH1A1L3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL9586748 | 0.80 | LMNA (0.47) | LMNACYP3A4ALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL9587330 | 0.80 | SLC6A2 (0.41) | LMNATBXAS1CYP3A4ALDH1A1SLC6A2 | |
| SCHEMBL9589519 | 0.79 | SMN1; SMN2 (0.43) | LMNASLC6A2SLC6A4SLC6A3L3MBTL1 | |
| SCHEMBL9587717 | 0.78 | LMNA (0.42) | LMNATBXAS1L3MBTL1CYP2D6CYP2C9 | |
| SCHEMBL9586338 | 0.76 | LMNA (0.39) | LMNATBXAS1CYP3A4ALDH1A1SLC6A2 | |
| SCHEMBL9586876 | 0.76 | TDP1 (0.43) | LMNATBXAS1L3MBTL1 | |
| SCHEMBL9587287 | 0.73 | LMNA (0.43) | LMNAALDH1A1L3MBTL1SMN1; SMN2FPR1 | |
| SCHEMBL19133210 | 0.72 | LMNA (0.37) | LMNAL3MBTL1CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL14339616 | 0.72 | MAOA (0.38) | LMNATBXAS1CYP3A4ALDH1A1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262420-A | Phenylalkylpyridines | IDEMITSU KOSAN CO., LTD. (JP) | 1993-11-16 | — | — | US | claimed |
| US-5262420-A | Phenylalkylpyridines | IDEMITSU KOSAN CO., LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0383950-A1 | PYRIDINE DERIVATIVES AND INSECTICIDAL AND MITICIDAL AGENT CONTAINING SAME AS ACTIVE INGREDIENT | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-08-29 | — | — | EP | disclosed |