SCHEMBL9588694

SCHEMBL9588694

COC(=O)c1sccc1S(=O)(=O)N(C(N)=NN)c1nc(C)cc(C)n1

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
EDNRA P25101 3/20 0.43
TP53 P04637 3/20 0.43
POLB P06746 1/20 0.41
LMNA P02545 5/20 0.41
MAPT P10636 4/20 0.40
THRB P10828 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9586075 0.85 EDNRA (0.41) EDNRATP53POLBLMNAMAPT
SCHEMBL9588686 0.82 CA1 (0.48) MAPTMEN1KMT2A
SCHEMBL9853104 0.81 MEN1 (0.43) EDNRATP53POLBLMNAMAPT
SCHEMBL7793855 0.77 EDNRA (0.41) EDNRATP53POLBLMNAMAPT
SCHEMBL9833690 0.75 EDNRA (0.46) EDNRATP53MAPTMEN1KMT2A
SCHEMBL9833684 0.75 EDNRA (0.46) EDNRATP53MAPTMEN1KMT2A
SCHEMBL9735496 0.74 EDNRA (0.41) EDNRATP53POLBLMNAMAPT
SCHEMBL9735502 0.74 EDNRA (0.41) EDNRATP53POLBLMNAMAPT
SCHEMBL9735514 0.74 EDNRA (0.45) EDNRATP53LMNAMAPTMEN1
SCHEMBL10502876 0.74 CA1 (0.44) POLBMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5092917-A HERBICIDAL AMINOGUANIDINOAZINES BAYER AKTIENGESELLSCHAFT (DE) 1992-03-03 US claimed
US-5211740-A Applying triazinyl sulfonylguanidine derivatives BAYER AKTIENGESELLSCHAFT (DE) 1993-05-18 US disclosed
US-5211740-A Applying triazinyl sulfonylguanidine derivatives BAYER AKTIENGESELLSCHAFT (DE) 1993-05-18 US disclosed
US-5092917-A HERBICIDAL AMINOGUANIDINOAZINES BAYER AKTIENGESELLSCHAFT (DE) 1992-03-03 US disclosed
US-5092917-A HERBICIDAL AMINOGUANIDINOAZINES BAYER AKTIENGESELLSCHAFT (DE) 1992-03-03 US disclosed
US-5091529-A HERBICIDAL SUBSTITUTED SULPHONYLAMINOAZOLES BAYER AKTIENGESELLSCHAFT (DE) 1992-02-25 US disclosed
US-5021082-A Pre=and postemergent BAYER AKTIENGESELLSCHAFT (DE) 1991-06-04 US disclosed
US-4941912-A Herbicidal substituted sulphonylaminoazoles BAYER AKTIENGESELLSCHAFT (DE) 1990-07-17 US disclosed
EP-0343462-A1 Aminoguanidino azines BAYER AG (DE) 1989-11-29 EP disclosed