Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735502 | 1.00 | EDNRA (0.41) | EDNRAMAPTTP53GAAL3MBTL1 | |
| SCHEMBL10437249 | 0.78 | EDNRA (0.46) | EDNRAMAPTGAAL3MBTL1ALDH1A1 | |
| SCHEMBL9735514 | 0.77 | EDNRA (0.45) | EDNRAMAPTTP53KDM4EMEN1 | |
| SCHEMBL9588694 | 0.74 | EDNRA (0.43) | EDNRAMAPTTP53MEN1KMT2A | |
| SCHEMBL9833690 | 0.74 | EDNRA (0.46) | EDNRAMAPTTP53KDM4EMEN1 | |
| SCHEMBL9833684 | 0.74 | EDNRA (0.46) | EDNRAMAPTTP53KDM4EMEN1 | |
| SCHEMBL9853099 | 0.74 | EDNRA (0.41) | EDNRAMAPTTP53ALDH1A1KDM4E | |
| SCHEMBL10754167 | 0.73 | EDNRA (0.49) | EDNRAMAPTGAAKDM4EMEN1 | |
| SCHEMBL9853104 | 0.72 | MEN1 (0.43) | EDNRAMAPTTP53GAAKDM4E | |
| SCHEMBL11471141 | 0.68 | EDNRA (0.52) | EDNRAMAPTTP53MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3031205-A | — | — | None | — | — | JP | disclosed |
| US-5091529-A | HERBICIDAL SUBSTITUTED SULPHONYLAMINOAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |
| US-5021082-A | Pre=and postemergent | BAYER AKTIENGESELLSCHAFT (DE) | 1991-06-04 | — | — | US | disclosed |
| EP-0419831-A2 | Substituted sulfonylaminoazoles | BAYER AG (DE) | 1991-04-03 | — | — | EP | disclosed |
| JP-H0331205-A | SULFONYLATED AMINOGUANIDINE-BASED HERBICIDE | BAYER AG | 1991-02-12 | — | — | JP | disclosed |
| US-4941912-A | Herbicidal substituted sulphonylaminoazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1990-07-17 | — | — | US | disclosed |
| EP-0330959-A2 | Substituted sulphonyl amino azoles | BAYER AG (DE) | 1989-09-06 | — | — | EP | disclosed |