SCHEMBL9735514

SCHEMBL9735514

COC(=O)c1sccc1S(=O)(=O)NC(N)=NNc1nc(C)cc(C)n1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EDNRA P25101 4/20 0.45
MAPT P10636 2/20 0.39
PPARG P37231 1/20 0.39
PPARD Q03181 1/20 0.39
PPARA Q07869 1/20 0.39
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
LMNA P02545 3/20 0.37
CCR2 P41597 1/20 0.37
TAS2R8 Q9NYW2 1/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CCKBR P32239 1/20 0.37
KCNH2 Q12809 1/20 0.37
TP53 P04637 1/20 0.36
HPGD P15428 2/20 0.36
KDM4E B2RXH2 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9833684 0.82 EDNRA (0.46) EDNRAMAPTPPARGPPARDPPARA
SCHEMBL9833690 0.82 EDNRA (0.46) EDNRAMAPTPPARGPPARDPPARA
SCHEMBL10754167 0.81 EDNRA (0.49) EDNRAMAPTPPARGPPARDPPARA
SCHEMBL10437249 0.78 EDNRA (0.46) EDNRAMAPTPPARGPPARDPPARA
SCHEMBL9735496 0.77 EDNRA (0.41) EDNRAMAPTPPARGPPARDPPARA
SCHEMBL9735502 0.77 EDNRA (0.41) EDNRAMAPTPPARGPPARDPPARA
SCHEMBL11117907 0.75 EDNRA (0.53) EDNRAMAPTPPARGPPARDPPARA
SCHEMBL10753757 0.75 GAA (0.50) EDNRAMAPTPPARGPPARDPPARA
SCHEMBL10747976 0.75 EDNRA (0.43) EDNRAMAPTPPARGPPARDPPARA
SCHEMBL9588694 0.74 EDNRA (0.43) EDNRAMAPTKMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3031205-A None JP disclosed
US-5091529-A HERBICIDAL SUBSTITUTED SULPHONYLAMINOAZOLES BAYER AKTIENGESELLSCHAFT (DE) 1992-02-25 US disclosed
US-5021082-A Pre=and postemergent BAYER AKTIENGESELLSCHAFT (DE) 1991-06-04 US disclosed
JP-H0331205-A SULFONYLATED AMINOGUANIDINE-BASED HERBICIDE BAYER AG 1991-02-12 JP disclosed
US-4941912-A Herbicidal substituted sulphonylaminoazoles BAYER AKTIENGESELLSCHAFT (DE) 1990-07-17 US disclosed