Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | EDNRA | P25101 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9588694 | 0.81 | EDNRA (0.43) | MEN1KMT2ATP53EDNRALMNA | |
| SCHEMBL9735502 | 0.72 | EDNRA (0.41) | MEN1KMT2ATP53EDNRALMNA | |
| SCHEMBL9735496 | 0.72 | EDNRA (0.41) | MEN1KMT2ATP53EDNRALMNA | |
| SCHEMBL9735514 | 0.72 | EDNRA (0.45) | MEN1KMT2ATP53EDNRALMNA | |
| SCHEMBL9833684 | 0.70 | EDNRA (0.46) | MEN1KMT2ATP53EDNRAMAPT | |
| SCHEMBL9853099 | 0.70 | EDNRA (0.41) | MEN1KMT2ATP53EDNRALMNA | |
| SCHEMBL9833690 | 0.70 | EDNRA (0.46) | MEN1KMT2ATP53EDNRAMAPT | |
| SCHEMBL9586075 | 0.69 | EDNRA (0.41) | MEN1KMT2ATP53EDNRALMNA | |
| SCHEMBL10754167 | 0.69 | EDNRA (0.49) | MEN1KMT2AEDNRAMAPTKDM4E | |
| SCHEMBL4358291 | 0.68 | CA1 (0.51) | MEN1KMT2ATP53EDNRALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419831-A2 | Substituted sulfonylaminoazoles | BAYER AG (DE) | 1991-04-03 | — | — | EP | disclosed |