Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9592290 | 0.91 | — | — | |
| SCHEMBL9590665 | 0.90 | PDE4A (0.39) | AGTR1AGTR2 | |
| SCHEMBL9590924 | 0.85 | AGTR2 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9590852 | 0.83 | PDE4A (0.43) | AGTR1 | |
| SCHEMBL9531226 | 0.82 | AGTR1 (0.35) | AGTR1AGTR2 | |
| SCHEMBL9592176 | 0.82 | PDE4A (0.48) | — | |
| SCHEMBL9591738 | 0.81 | GSK3B (0.50) | GSK3BAGTR2 | |
| SCHEMBL9044905 | 0.80 | GSK3B (0.46) | GSK3BAGTR1AGTR2 | |
| SCHEMBL9592923 | 0.80 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9592046 | 0.80 | PDE4A (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264439-A | Quinazolinone, triazolinone and pyrimidinone angiotensin II antagonists incorporating a substituted benzyl element | MERCK & CO., INC. (US) | 1993-11-23 | — | — | US | disclosed |