Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 2/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9590665 | 0.95 | PDE4A (0.39) | AGTR2AGTR1 | |
| SCHEMBL9592923 | 0.85 | AGTR1 (0.41) | AGTR2AGTR1 | |
| SCHEMBL9592404 | 0.85 | NPC1 (0.45) | — | |
| SCHEMBL9592014 | 0.85 | GSK3B (0.46) | AGTR2AGTR1 | |
| SCHEMBL9591379 | 0.84 | AGTR2 (0.41) | AGTR2AGTR1 | |
| SCHEMBL9592120 | 0.84 | AGTR1 (0.38) | AGTR2AGTR1 | |
| SCHEMBL9591498 | 0.83 | AGTR1 (0.43) | AGTR2AGTR1 | |
| SCHEMBL9592770 | 0.83 | AGTR1 (0.39) | AGTR2AGTR1 | |
| SCHEMBL9532231 | 0.82 | — | — | |
| SCHEMBL9592109 | 0.82 | AGTR1 (0.37) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264439-A | Quinazolinone, triazolinone and pyrimidinone angiotensin II antagonists incorporating a substituted benzyl element | MERCK & CO., INC. (US) | 1993-11-23 | — | — | US | disclosed |