SCHEMBL959288

SCHEMBL959288

CCO[Ti](OCC)(OCC)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.37
TP53 P04637 1/20 0.36
RELA Q04206 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
KCNH2 Q12809 1/20 0.32
GLA P06280 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
PSIP1 O75475 1/20 0.31
NQO1 P15559 1/20 0.31
CA4 P22748 1/20 0.31
PIN1 Q13526 1/20 0.31
POLB P06746 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6151854 0.80 LTA4H (0.37) LTA4HTP53RELANPSR1L3MBTL1
SCHEMBL5531479 0.78 LTA4H (0.35) LTA4HTP53RELANPSR1L3MBTL1
SCHEMBL15453497 0.78 LTA4H (0.35) LTA4HTP53RELANPSR1L3MBTL1
SCHEMBL19713179 0.78 ACHE (0.38) ALDH1A1MEN1KMT2AACHE
SCHEMBL482784 0.76 CA4 (0.41) LTA4HALDH1A1TSHRKMT2ACA4
SCHEMBL3614968 0.75 ALDH1A1 (0.38) NPSR1ALDH1A1TSHRMEN1KMT2A
SCHEMBL6915639 0.67 TP53 (0.44) LTA4HTP53ALDH1A1TSHR
SCHEMBL6911286 0.67 TP53 (0.44) LTA4HTP53ALDH1A1TSHR
SCHEMBL9062579 0.67 LTA4H (0.43) LTA4HTP53RELAL3MBTL1TSHR
SCHEMBL6912983 0.67 TP53 (0.44) LTA4HTP53ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10144848-B2 Thermally curable coating systems NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2018-12-04 US claimed
US-10144817-B2 Active and intelligent additive, polymer and article Brasksm S.A. (BR) 2018-12-04 US claimed
EP-2999753-B1 THERMALLY CURABLE COATING SYSTEMS TNO (NL) 2018-07-25 EP claimed
EP-2617764-B1 AN ADDITIVE, A POLYMER AND AN ARTICLE THAT ARE ACTIVE AND INTELLIGENT BRASKEM SA (BR) 2018-01-10 EP claimed
US-20170283592-A1 ACTIVE AND INTELLIGENT ADDITIVE, POLYMER AND ARTICLE BRASKEM S.A. (BR) 2017-10-05 US claimed
US-9700054-B2 Active and intelligent additive, polymer and article BRASKEM S.A. (BR) 2017-07-11 US claimed
US-20160122584-A1 THERMALLY CURABLE COATING SYSTEMS NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2016-05-05 US claimed
CN-105452393-A Thermally curable coating systems NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO 2016-03-30 CN claimed
US-9063111-B2 Hybrid chemical sensor, and, sensitive polymeric composition BRASKEM S.A. (BR) 2015-06-23 US claimed
EP-2808364-A1 Thermally curable coating systems Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO (NL) 2014-12-03 EP claimed
US-20130266626-A1 ACTIVE AND INTELLIGENT ADDITIVE, POLYMER AND ARTICLE UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL (BR) 2013-10-10 US claimed
EP-2617764-A1 ACTIVE AND INTELLIGENT ADDITIVE, POLYMER AND ARTICLE Braskem S.A. (BR) 2013-07-24 EP claimed
US-20130040152-A1 PROCESS VIA EXTRUSION FOR PREPARING A HYBRID POLYMER COMPOSITION, HYBRID POLYMER COMPOSITION AND ARTICLE BRASKEM S.A. (BR) 2013-02-14 US claimed
EP-2487200-A1 EXTRUSION METHOD FOR PRODUCING A HYBRID POLYMER COMPOSITION, HYBRID POLYMER COMPOSITION AND ARTICLE Braskem S.A. (BR) 2012-08-15 EP claimed
US-20120009687-A1 HYBRID CHEMICAL SENSOR, AND, SENSITIVE POLYMERIC COMPOSITION UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL (BR) 2012-01-12 US claimed
WO-2010001298-A1 CHEMICAL SENSORS MODIFIED BY THE SOL-GEL METHOD AND ITS APPLICATION TO POLYMERIC MATRIXES BRASKEM S.A. (BR) 2010-01-07 WO claimed
US-20240030448-A1 CONDUCTIVE MATERIAL DISPERSION, AND METHODS FOR MANUFACTURING POSITIVE ELECTRODE FOR LITHIUM ION SECONDARY BATTERY AND LITHIUM ION SECONDARY BATTERY USING SAME MIKUNI SHIKISO KABUSHIKI KAISHA (JP) 2024-01-25 US disclosed
CN-112657447-B Chemical conversion process 荷兰应用自然科学研究组织TNO 2023-02-17 CN disclosed
EP-0938972-A1 Photosensitive lithographic form plate using an image-forming material FUJI PHOTO FILM CO., LTD. (JP) 1999-09-01 EP disclosed
EP-0903224-A2 Radiation-sensitive planographic plate FUJI PHOTO FILM CO., LTD. (JP) 1999-03-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130266626-A1 ACTIVE AND INTELLIGENT ADDITIVE, POLYMER AND ARTICLE AAAS, PIM1, PIM3 LTA4H 2747/4885TP53 1233/4885RELA 3354/4885
US-20170283592-A1 ACTIVE AND INTELLIGENT ADDITIVE, POLYMER AND ARTICLE AAAS, PIM1, PIM3 LTA4H 2747/4885TP53 1233/4885RELA 3354/4885
US-10144817-B2 Active and intelligent additive, polymer and article AAAS, PIM1, PIM3 LTA4H 2747/4885TP53 1233/4885RELA 3354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.