Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.71 |
| ▸ | HTR2C | P28335 | 4/20 | 0.71 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 6/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 3/20 | 0.55 |
| ▸ | HTR7 | P34969 | 4/20 | 0.54 |
| ▸ | DRD5 | P21918 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9594603 | 0.94 | HTR1A (0.69) | HTR1AHTR2CSIGMAR1DRD2DRD3 | |
| SCHEMBL9594420 | 0.86 | DRD4 (0.74) | HTR1AHTR2CSIGMAR1DRD2DRD3 | |
| SCHEMBL9594629 | 0.83 | HTR1A (1.00) | HTR1AHTR2CSIGMAR1DRD2DRD3 | |
| SCHEMBL8786686 | 0.83 | DRD2 (0.60) | HTR1AHTR2CSIGMAR1DRD2DRD3 | |
| SCHEMBL9659923 | 0.83 | HTR1A (0.65) | HTR1AHTR2CSIGMAR1DRD2HTR2A | |
| SCHEMBL6903300 | 0.81 | DRD4 (0.74) | HTR1AHTR2CSIGMAR1DRD2DRD3 | |
| SCHEMBL9594197 | 0.79 | DRD4 (0.79) | HTR1AHTR2CSIGMAR1DRD2DRD3 | |
| SCHEMBL10864650 | 0.79 | DRD2 (0.74) | HTR1AHTR2CSIGMAR1DRD2DRD3 | |
| SCHEMBL8787679 | 0.78 | DRD2 (0.53) | HTR1AHTR2CSIGMAR1DRD2DRD3 | |
| SCHEMBL8948129 | 0.77 | HTR1A (0.70) | HTR1AHTR2CSIGMAR1DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225409-A | Serotoninergic disorders; anxiolytic agents; schizophrenia | ADIR ET COMPAGNIE (FR) | 1993-07-06 | — | — | US | claimed |