Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4078697 | 0.88 | GBA2 (0.41) | GBA2LMNAPOLBSMN1; SMN2ECE1 | |
| SCHEMBL9595391 | 0.85 | LMNA (0.36) | GBA2LMNAPOLBSMN1; SMN2ECE1 | |
| SCHEMBL8106554 | 0.83 | ABCB1 (0.35) | — | |
| SCHEMBL9595418 | 0.83 | ABCB1 (0.35) | — | |
| SCHEMBL9026745 | 0.83 | CYP19A1 (0.32) | — | |
| SCHEMBL9026747 | 0.83 | CYP19A1 (0.32) | — | |
| SCHEMBL9026899 | 0.83 | CYP19A1 (0.32) | — | |
| SCHEMBL9026904 | 0.83 | CYP19A1 (0.32) | — | |
| SCHEMBL4416435 | 0.82 | PPM1D (0.33) | — | |
| SCHEMBL22980252 | 0.81 | GBA2 (0.36) | GBA2LMNAPOLBSMN1; SMN2ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993011128-A1 | AMINOALKYLPYRROLIDINYLTHIOCARBAPENEM DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-10 | — | — | WO | disclosed |