Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9593843 | 0.86 | LMNA (0.53) | NQO2ALDH1A1KDM4ESMN1; SMN2RAD52 | |
| SCHEMBL9593890 | 0.84 | NQO2 (0.47) | NQO2ALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL9593499 | 0.84 | PDE3B (0.46) | NQO2ALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL9594269 | 0.84 | NQO2 (0.47) | NQO2ALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL9593780 | 0.80 | POLB (0.51) | NQO2ALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL9593472 | 0.80 | MPO (0.47) | NQO2ALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL9594784 | 0.76 | PDE3B (0.46) | NQO2ALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL9593886 | 0.76 | PDE3B (0.46) | NQO2ALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL9724203 | 0.75 | MAPT (0.63) | NQO2ALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL8139053 | 0.75 | ALDH1A1 (0.41) | NQO2ALDH1A1KDM4ESMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005770-A1 | POTENTIAL ANTICANCER AGENTS DERIVED FROM ACRIDINE | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1991-05-02 | — | — | WO | claimed |
| US-5229395-A | Potential anticancer agents derived from acridine | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1993-07-20 | — | — | US | disclosed |
| WO-1991005770-A1 | POTENTIAL ANTICANCER AGENTS DERIVED FROM ACRIDINE | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1991-05-02 | — | — | WO | disclosed |