SCHEMBL9595463

SCHEMBL9595463

CC(=O)NC1(C(=O)O)CCCC1.Cc1cccc(C)c1C

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
CXCR5 P32302 3/20 0.41
PYGL P06737 5/20 0.41
CYP2C9 P11712 1/20 0.40
HDAC4 P56524 3/20 0.40
FABP4 P15090 3/20 0.39
FABP5 Q01469 3/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9594339 0.98 PYGL (0.42) ALDH1A1CXCR5PYGLCYP2C9HDAC4
SCHEMBL1573844 0.82 FFAR3 (0.40) ALDH1A1PYGLFABP4FABP5MAPT
SCHEMBL3704763 0.80 FFAR3 (0.39) ALDH1A1PYGLCYP2C9FABP4FABP5
SCHEMBL9613093 0.78 FFAR3 (0.40) ALDH1A1PYGLFABP4FABP5
SCHEMBL1839139 0.77 ALDH1A1 (0.40) ALDH1A1CXCR5PYGLCYP2C9MAPT
SCHEMBL1839140 0.77 ALDH1A1 (0.40) ALDH1A1CXCR5PYGLCYP2C9MAPT
SCHEMBL13164041 0.76 PYGL (0.54) CXCR5PYGLCYP2C9
SCHEMBL3985967 0.74 FFAR3 (0.43) ALDH1A1PYGLFABP4FABP5
SCHEMBL1840989 0.73 MEN1 (0.61) PYGLCYP2C9FABP4FABP5
Acetic Acid SCHEMBL3662435 0.72 TRPA1 (0.52) ALDH1A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5258527-A Insecticidal, acaricidal and herbicidal 1-H-3-aryl-pyrrolidine-2,4-dione derivatives BAYER AKTIENGESELLSCHAFT (DE) 1993-11-02 US disclosed