Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587827 | 0.81 | NPSR1 (0.46) | KMT2AMEN1RAB9ANPC1ATM | |
| SCHEMBL9603546 | 0.79 | KMT2A (0.41) | KMT2AMEN1RAB9ANPC1ATM | |
| SCHEMBL10862964 | 0.76 | NOS3 (0.48) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14182349 | 0.72 | KMT2A (0.50) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL1861757 | 0.72 | RAB9A (0.55) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11712255 | 0.72 | RAB9A (0.55) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10861598 | 0.71 | KMT2A (0.43) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4581966 | 0.70 | KMT2A (0.57) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10730622 | 0.69 | MAPT (0.57) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1023541 | 0.69 | MEN1 (1.00) | KMT2AMEN1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016070-A1 | 3-(PYRIDYLAMINO)-2-(1H^_-TETRAZOL-5-YL)-ACRYLNITRILES AND A PROCESS FOR THE PREPARATION THEREOF | CHINOIN GYÓGYSZER- ÉS VEGYÉSZETI TERMÉKEK GYÁRA RT. (HU) | 1993-08-19 | — | — | WO | disclosed |
| EP-0174832-A2 | Ethene derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |