Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 5/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10699439 | 0.83 | TDP1 (0.39) | DPP8DPP9HTR2AALDH1A1MAPT | |
| SCHEMBL8106414 | 0.83 | DPP8 (0.44) | DPP8DPP9TGM2CTSLALDH1A1 | |
| SCHEMBL9596093 | 0.82 | DPP8 (0.47) | DPP8DPP9TGM2ALDH1A1MAPT | |
| SCHEMBL10858260 | 0.79 | DPP8 (0.41) | DPP8DPP9HTR2AALDH1A1MAPT | |
| SCHEMBL8112372 | 0.79 | TGM2 (0.41) | DPP8DPP9TGM2CTSLHTR2A | |
| SCHEMBL9521309 | 0.78 | ALDH1A1 (0.39) | DPP8DPP9HTR2AALDH1A1MAPT | |
| SCHEMBL10699226 | 0.77 | ALDH1A1 (0.40) | DPP8DPP9HTR2AALDH1A1MAPT | |
| SCHEMBL10697655 | 0.76 | TDP1 (0.40) | DPP8DPP9HTR2AALDH1A1MAPT | |
| SCHEMBL10698245 | 0.76 | TDP1 (0.42) | DPP8DPP9HTR2AALDH1A1MAPT | |
| SCHEMBL9519946 | 0.76 | TDP1 (0.41) | HTR2AALDH1A1MAPTHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993011128-A1 | AMINOALKYLPYRROLIDINYLTHIOCARBAPENEM DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-10 | — | — | WO | disclosed |