Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CCR8 | P51685 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17483520 | 0.85 | STS (0.47) | KMT2AL3MBTL1 | |
| SCHEMBL24104500 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL26386510 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL9344787 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL24104493 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL30608221 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL26386513 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL29889592 | 0.81 | ABL1 (0.46) | ELANE | |
| SCHEMBL8741021 | 0.79 | L3MBTL1 (0.47) | ALDH1A1L3MBTL1CCR8 | |
| SCHEMBL6356905 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179090-A | Antiischemic agents; treatment of asthma, bronchitis, heart diseases | DR. KARL THOMAE GMBH (DE) | 1993-01-12 | — | — | US | disclosed |
| EP-0417630-A2 | Condensed diazepinones, process for their preparation, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1991-03-20 | — | — | EP | disclosed |