Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 8/20 | 0.68 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9596201 | 1.00 | GRIN2B (0.68) | GRIN2BGRIN1LMNATSHRHIF1A | |
| SCHEMBL9212054 | 0.75 | GPR52 (0.41) | GRIN2BGRIN1LMNATSHRHIF1A | |
| [11C]Phenethylguanidine SCHEMBL837645 | 0.72 | HTR3A (0.80) | GRIN2BGRIN1LMNATSHRHIF1A | |
| SCHEMBL9153569 | 0.71 | GRIN1 (0.71) | GRIN2BGRIN1LMNATSHRHIF1A | |
| SCHEMBL1544143 | 0.69 | — | — | |
| SCHEMBL15574231 | 0.69 | GPR52 (0.57) | MAPTSMN1; SMN2TDP1GPR52GAA | |
| SCHEMBL5839538 | 0.69 | HIF1A (0.65) | GRIN2BGRIN1LMNATSHRHIF1A | |
| SCHEMBL14625427 | 0.68 | — | — | |
| SCHEMBL27447143 | 0.68 | NOS3 (0.54) | ADRA2AADRA2BSLC6A2TDP1HTR3A | |
| Hydrochloric Acid SCHEMBL10876994 | 0.67 | HIF1A (0.62) | GRIN2BGRIN1LMNATSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5272164-A | Carboximidamide derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1993-12-21 | — | — | US | disclosed |