Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300884 | 0.86 | CA12 (0.42) | ALDH1A1HPGDKMT2AMEN1KDM4E | |
| SCHEMBL9743869 | 0.85 | HPGD (0.38) | ALDH1A1HPGDKMT2AMEN1LOXL2 | |
| SCHEMBL17071632 | 0.85 | ALDH1A1 (0.47) | ALDH1A1HPGDKMT2AMEN1LOXL2 | |
| SCHEMBL13845025 | 0.84 | LOXL2 (0.53) | ALDH1A1HPGDKMT2AMEN1LOXL2 | |
| SCHEMBL17208731 | 0.84 | CA1 (0.44) | ALDH1A1HPGDKMT2AMEN1KDM4E | |
| SCHEMBL20278541 | 0.83 | ALDH1A1 (0.40) | ALDH1A1HPGDKMT2AMEN1KDM4E | |
| SCHEMBL16426741 | 0.82 | LOXL2 (0.40) | ALDH1A1KMT2ALOXL2MGLL | |
| SCHEMBL1800956 | 0.81 | PTPRF (0.44) | CES2CES1ALDH1A1HPGDKDM4E | |
| SCHEMBL8759248 | 0.81 | CA2 (0.43) | ALDH1A1HPGDKMT2AMEN1LOXL2 | |
| SCHEMBL20278536 | 0.81 | POLB (0.41) | ALDH1A1HPGDKMT2AMEN1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3408349-B1 | CHEMILUMINESCENT FLUOROPHOR-LINKED ADAMANTYLENE-DIOXETANE PROBES AS DIAGNOSTICS OR IN-VIVO IMAGING SENSORS | UNIV RAMOT (IL) | 2021-03-31 | — | — | EP | disclosed |
| WO-2017130191-A1 | CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2017-08-03 | — | — | WO | disclosed |
| US-5248770-A | Labels such as fluorescent or radioactive compounds | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1993-09-28 | — | — | US | disclosed |
| US-5098996-A | Fluorination of compounds for use in diagnosis of nuclear medicine | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1992-03-24 | — | — | US | disclosed |