Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9613886 | 0.94 | MAPT (0.61) | MAPTTDP1KMT2AMEN1NPC1 | |
| SCHEMBL9596806 | 0.83 | MAPT (0.51) | MAPTTDP1KMT2AMEN1NPC1 | |
| SCHEMBL21225808 | 0.81 | MAPT (0.90) | MAPTTDP1KMT2AMEN1NPC1 | |
| SCHEMBL9603353 | 0.81 | HTR2A (0.48) | MAPTTDP1KMT2AMEN1NPC1 | |
| SCHEMBL9517046 | 0.81 | MAPT (0.54) | MAPTTDP1KMT2AMEN1NPC1 | |
| SCHEMBL735125 | 0.78 | MAPT (1.00) | MAPTTDP1KMT2AMEN1NPC1 | |
| SCHEMBL14625611 | 0.77 | KMT2A (0.67) | MAPTTDP1KMT2AMEN1NPC1 | |
| SCHEMBL7863739 | 0.76 | HTR2A (0.68) | MAPTTDP1KMT2AMEN1HTR2A | |
| SCHEMBL19134154 | 0.76 | HTR2A (0.68) | MAPTTDP1KMT2AMEN1HTR2A | |
| SCHEMBL19134209 | 0.76 | HTR2A (0.68) | MAPTTDP1KMT2AMEN1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250538-A | Treating CNS disorders; antiserotinin agents | NOVO NORDISK A/S (DK) | 1993-10-05 | — | — | US | disclosed |