Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR1E | P28566 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9596924 | 0.83 | MAPT (0.67) | MAPTHTR2ATDP1KMT2AMEN1 | |
| SCHEMBL9603353 | 0.83 | HTR2A (0.48) | MAPTHTR2ATDP1KMT2AMEN1 | |
| SCHEMBL9517210 | 0.82 | MAPT (0.42) | MAPTHTR2ATDP1HTR1AALDH1A1 | |
| Oxalic Acid SCHEMBL9613886 | 0.79 | MAPT (0.61) | MAPTHTR2ATDP1KMT2AMEN1 | |
| SCHEMBL7863739 | 0.72 | HTR2A (0.68) | MAPTHTR2ATDP1KMT2AMEN1 | |
| SCHEMBL19134209 | 0.72 | HTR2A (0.68) | MAPTHTR2ATDP1KMT2AMEN1 | |
| SCHEMBL19134154 | 0.72 | HTR2A (0.68) | MAPTHTR2ATDP1KMT2AMEN1 | |
| SCHEMBL9517255 | 0.72 | SMN1; SMN2 (0.50) | MAPTHTR2AKMT2AMEN1LMNA | |
| SCHEMBL28417220 | 0.71 | HTR2A (0.71) | MAPTHTR2ATDP1KMT2AMEN1 | |
| SCHEMBL25811714 | 0.71 | HTR2A (0.67) | MAPTHTR2ATDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250538-A | Treating CNS disorders; antiserotinin agents | NOVO NORDISK A/S (DK) | 1993-10-05 | — | — | US | disclosed |
| US-5126363-A | Central nervous system disorders | NOVO NORDISK A/S (DK) | 1992-06-30 | — | — | US | disclosed |