Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.43 |
| ▸ | SLC6A4 known ✓ | P31645 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 4/20 | 0.43 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1740285 | 0.94 | SLC6A4 (0.47) | SCN9AACHEUSP2CYP3A4CYP1A2 | |
| Oxalic Acid SCHEMBL9596772 | 0.86 | ATM (0.51) | SCN9AACHEOPRM1OPRD1OPRK1 | |
| Oxalic Acid SCHEMBL9596513 | 0.85 | SLC6A9 (0.47) | SCN9AACHEMGLLALDH1A1TDP1 | |
| Oxalic Acid SCHEMBL9597259 | 0.85 | OPRM1 (0.50) | SCN9AUSP2OPRM1OPRD1OPRK1 | |
| SCHEMBL10848810 | 0.81 | SLC6A4 (0.45) | CYP2D6OPRM1OPRK1MGLLABHD6 | |
| SCHEMBL1769006 | 0.79 | SLC6A3 (0.46) | SCN9AACHEUSP2CYP3A4CYP1A2 | |
| SCHEMBL795699 | 0.78 | ACHE (0.45) | SCN9AACHEOPRM1OPRD1OPRK1 | |
| SCHEMBL9596721 | 0.78 | SLC6A2 (0.47) | SCN9AACHEOPRM1OPRD1OPRK1 | |
| SCHEMBL1740319 | 0.78 | SLC6A4 (0.47) | CYP2D6OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9596460 | 0.78 | SLC6A2 (0.47) | USP2CYP3A4CYP1A2CYP2D6OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5183902-A | Muscle relaxants | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-02-02 | — | — | US | disclosed |
| US-5151418-A | Muscle relaxants | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-09-29 | — | — | US | disclosed |
| US-5068231-A | Ureas and thioureas for relaxing muscles | A. H. ROBINS COMPANY INCORPORATED (US) | 1991-11-26 | — | — | US | disclosed |
| US-4956359-A | CARBOXAMIDES OR THIOCARBOXAMIDES OF ARYL OXY OR THIO AZETIDINES | A. H. ROBINS COMPANY, INC. (US) | 1990-09-11 | — | — | US | disclosed |