Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9599077 | 0.80 | TP53 (0.43) | LMNA | |
| SCHEMBL4859756 | 0.80 | NPY5R (0.55) | DRD3MTNR1AMTNR1BNPY5RNOTUM | |
| SCHEMBL9597226 | 0.80 | ALOX5 (0.44) | DRD3NPY5R | |
| SCHEMBL27731472 | 0.78 | DRD3 (0.43) | DRD3MTNR1AMTNR1BNPY5RNOTUM | |
| SCHEMBL14590475 | 0.76 | DRD3 (0.49) | DRD3MTNR1AMTNR1BHTR1A | |
| SCHEMBL13209058 | 0.73 | NPY5R (0.60) | DRD3MTNR1AMTNR1BNPY5RMEN1 | |
| SCHEMBL8725635 | 0.73 | DRD3 (0.42) | DRD3MTNR1AMTNR1BNPY5RHTR1A | |
| SCHEMBL14685832 | 0.71 | NPY5R (0.50) | DRD3MTNR1AMTNR1BNPY5RHTR1A | |
| SCHEMBL7120391 | 0.70 | SPHK1 (0.38) | DRD3MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL434294 | 0.70 | MTNR1A (0.47) | MTNR1AMTNR1BNOTUMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5256789-A | Antiinflammatory hydroxamic acids and N-hydroxyureas | PFIZER INC. (US) | 1993-10-26 | — | — | US | disclosed |
| WO-1991016298-A1 | ANTIINFLAMMATORY HYDROXAMIC ACIDS AND N-HYDROXYUREAS | PFIZER INC (US) | 1991-10-31 | — | — | WO | disclosed |