Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9597211 | 0.85 | ALOX5 (0.46) | TP53MAOBNISCH | |
| SCHEMBL9596997 | 0.80 | DRD3 (0.44) | LMNA | |
| SCHEMBL28149605 | 0.76 | TP53 (0.43) | TP53MAOBNISCH | |
| SCHEMBL10205890 | 0.74 | TP53 (0.56) | TP53MAOB | |
| SCHEMBL7439814 | 0.72 | DRD2 (0.44) | TP53 | |
| SCHEMBL27904456 | 0.71 | MTNR1A (0.63) | TP53LMNAPOLB | |
| SCHEMBL27904454 | 0.71 | MTNR1A (0.63) | TP53LMNAPOLB | |
| SCHEMBL9441763 | 0.71 | DRD3 (0.65) | — | |
| Hydrochloric Acid SCHEMBL10701294 | 0.70 | DRD3 (0.63) | — | |
| SCHEMBL4980691 | 0.69 | TP53 (0.53) | TP53MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5256789-A | Antiinflammatory hydroxamic acids and N-hydroxyureas | PFIZER INC. (US) | 1993-10-26 | — | — | US | disclosed |