Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9599313 | 0.88 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL9599300 | 0.86 | SMN1; SMN2 (0.40) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL9597646 | 0.80 | ENPP1 (0.41) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL9597826 | 0.79 | ALK (0.41) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL9597622 | 0.78 | ENPP1 (0.38) | ALDH1A1MEN1KMT2AGAAMAPT | |
| Hydrochloric Acid SCHEMBL9597614 | 0.77 | HRH3 (0.43) | — | |
| SCHEMBL9599082 | 0.77 | HTT (0.42) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9599177 | 0.73 | RAPGEF4 (0.41) | ALDH1A1MEN1KMT2AGAAKDM4E | |
| Hydrochloric Acid SCHEMBL9603646 | 0.71 | HRH3 (0.49) | ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL4157574 | 0.71 | ENPP2 (0.39) | ALDH1A1MEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5182291-A | Angina pectoris, hypotensive, antiarrhythmia, cerebral vascular insufficiency | SANOFI (FR) | 1993-01-26 | — | — | US | disclosed |
| US-5147878-A | Hypotensive, antiarrhythmia agents | SANOFI (FR) | 1992-09-15 | — | — | US | disclosed |
| US-5039700-A | Cardiovascular disorders, antitumor agents | SANOFI (FR) | 1991-08-13 | — | — | US | disclosed |
| US-5017579-A | Use of aminoalkoxyphenyl derivatives for reducing and/or controlling excessive intraocular pressure | SANOFI (FR) | 1991-05-21 | — | — | US | disclosed |
| US-4957925-A | HYPOTENSIVE AGENTS, ANTIARRHYTHMIA AGENTS, TREATMENT OF ANGINA | SANOFI (FR) | 1990-09-18 | — | — | US | disclosed |