Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9600719 | 0.89 | PLA2G2A (0.38) | GRM5L3MBTL1PLA2G2ANPC1RAB9A | |
| SCHEMBL9600689 | 0.87 | PLA2G2A (0.42) | GRM5PLA2G2ANPC1RAB9ABCHE | |
| SCHEMBL9600841 | 0.86 | PLA2G2A (0.44) | GRM5PLA2G2ANPC1RAB9ABCHE | |
| SCHEMBL4018144 | 0.84 | GAA (0.39) | L3MBTL1POLB | |
| SCHEMBL11493479 | 0.73 | HDAC3 (0.36) | — | |
| SCHEMBL9602154 | 0.73 | MEN1 (0.32) | — | |
| SCHEMBL609688 | 0.69 | L3MBTL1 (0.42) | L3MBTL1NPC1RAB9APOLBBCHE | |
| SCHEMBL22017464 | 0.69 | L3MBTL1 (0.34) | GRM5L3MBTL1PKN2POLB | |
| SCHEMBL29019612 | 0.69 | L3MBTL1 (0.34) | L3MBTL1POLB | |
| SCHEMBL9600392 | 0.69 | L3MBTL1 (0.38) | GRM5L3MBTL1PKN2POLBBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215435-B1 | 2-OXA-ISOCEPHEM COMPOUNDS, COMPOSITIONS CONTAINING SAME AND PROCESSES FOR PREPARING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-4831026-A | ANTIBIOTICS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0215435-A1 | 2-Oxa-isocephem compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-03-25 | — | — | EP | disclosed |