Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9600689 | 0.95 | PLA2G2A (0.42) | PLA2G2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9600841 | 0.93 | PLA2G2A (0.44) | PLA2G2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9600407 | 0.89 | GRM5 (0.35) | PLA2G2ANPC1RAB9AGRM5BCHE | |
| SCHEMBL4018144 | 0.81 | GAA (0.39) | SMN1; SMN2ALOX15GAAPOLBL3MBTL1 | |
| SCHEMBL4424409 | 0.72 | MEN1 (0.45) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL2245662 | 0.71 | LMNA (0.40) | PLA2G2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13572995 | 0.71 | ALDH1A1 (0.38) | PLA2G2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9600708 | 0.71 | ALDH1A1 (0.38) | PLA2G2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11493479 | 0.70 | HDAC3 (0.36) | — | |
| SCHEMBL9602154 | 0.70 | MEN1 (0.32) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215435-B1 | 2-OXA-ISOCEPHEM COMPOUNDS, COMPOSITIONS CONTAINING SAME AND PROCESSES FOR PREPARING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-4831026-A | ANTIBIOTICS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0215435-A1 | 2-Oxa-isocephem compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-03-25 | — | — | EP | disclosed |