SCHEMBL96008

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14018752	0.82	ALDH1A1 (0.68)	L3MBTL1HSD17B1HSD17B2PGRLMNA
	SCHEMBL3273156	0.80	L3MBTL1 (0.55)	L3MBTL1HSD17B1HSD17B2LMNAALDH1A1
	SCHEMBL95688	0.79	PKM (0.60)	PGRLMNAALDH1A1MEN1KMT2A
	SCHEMBL94976	0.79	MAPT (0.54)	PGRLMNAALDH1A1SMN1; SMN2MEN1
	SCHEMBL94831	0.78	MAPT (0.63)	LMNAALDH1A1MEN1KMT2ACDK1
	SCHEMBL95927	0.78	ALDH1A1 (0.67)	L3MBTL1LMNAALDH1A1SMN1; SMN2MEN1
	SCHEMBL12584959	0.78	POLB (0.62)	PGRLMNAALDH1A1GAASMN1; SMN2
	SCHEMBL95834	0.76	BRD4 (0.51)	HSD17B2LMNASMN1; SMN2MEN1KMT2A
	SCHEMBL3268117	0.76	L3MBTL1 (0.51)	L3MBTL1HSD17B1HSD17B2PGRLMNA
	SCHEMBL95032	0.76	HSD11B1 (0.59)	PGRALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.