SCHEMBL960081

SCHEMBL960081

C=C(C)c1ccccc1C[SiH](OC)OC

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
CYP2C9 P11712 1/20 0.32
HIF1A Q16665 1/20 0.32
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2513310 0.76 ALDH1A1 (0.39) ALDH1A1LMNAHPGDTSHR
SCHEMBL3284499 0.74 ALDH1A1 (0.43) ALDH1A1LMNATSHR
SCHEMBL8980481 0.73 ALDH1A1 (0.36) ALDH1A1LMNAHPGDTSHR
SCHEMBL721894 0.72 GABRA1 (0.44) ALDH1A1LMNAHPGDTSHR
SCHEMBL29396009 0.72 GABRA1 (0.44) ALDH1A1LMNAHPGDTSHR
SCHEMBL1066307 0.72 LMNA (0.43) ALDH1A1LMNACYP2C9HPGDTSHR
SCHEMBL8037773 0.71 ALDH1A1 (0.33) ALDH1A1LMNA
SCHEMBL18528783 0.71 ALDH1A1 (0.39) ALDH1A1LMNAHPGDTSHR
SCHEMBL19502268 0.71 ALDH1A1 (0.33) ALDH1A1LMNAHPGD
SCHEMBL63870 0.71 ALDH1A1 (0.41) ALDH1A1CYP2C9HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110000658-A1 HYDROPHILIC MEMBER FUJIFILM CORPORATION (JP) 2011-01-06 US disclosed
EP-2239137-A1 HYDROPHILIC MEMBERS FUJIFILM Corporation (JP) 2010-10-13 EP disclosed