Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | MGLL | Q99685 | 3/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9600683 | 0.98 | PLA2G2A (0.40) | PLA2G2AGBA1BCHEACHEALDH1A1 | |
| SCHEMBL9600708 | 0.93 | ALDH1A1 (0.38) | PLA2G2AGBA1BCHEACHEALDH1A1 | |
| SCHEMBL9600392 | 0.86 | L3MBTL1 (0.38) | BCHEACHEGRM5 | |
| SCHEMBL4018142 | 0.78 | GAA (0.39) | SMN1; SMN2GAAALOX15 | |
| SCHEMBL31093244 | 0.74 | GBA1 (0.47) | PLA2G2AGBA1BCHEACHEALDH1A1 | |
| SCHEMBL31093212 | 0.74 | GBA1 (0.47) | PLA2G2AGBA1BCHEACHEALDH1A1 | |
| SCHEMBL9769271 | 0.74 | GBA1 (0.47) | PLA2G2AGBA1BCHEACHEALDH1A1 | |
| SCHEMBL9769185 | 0.74 | GBA1 (0.47) | PLA2G2AGBA1BCHEACHEALDH1A1 | |
| SCHEMBL9617015 | 0.74 | GBA1 (0.47) | PLA2G2AGBA1BCHEACHEALDH1A1 | |
| SCHEMBL5924538 | 0.73 | MGLL (0.39) | PLA2G2AGBA1ALDH1A1ALOX5PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215435-B1 | 2-OXA-ISOCEPHEM COMPOUNDS, COMPOSITIONS CONTAINING SAME AND PROCESSES FOR PREPARING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-4831026-A | ANTIBIOTICS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0215435-A1 | 2-Oxa-isocephem compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-03-25 | — | — | EP | disclosed |