Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18727407 | 0.84 | LMNA (0.38) | SIGMAR1LMNACNR1ADRA1ATDP1 | |
| SCHEMBL10648742 | 0.79 | LMNA (0.46) | SIGMAR1LMNACNR1ADRA1ATDP1 | |
| SCHEMBL16145722 | 0.78 | — | — | |
| SCHEMBL2484735 | 0.75 | LMNA (0.54) | SIGMAR1LMNACNR1ADRA1ATDP1 | |
| SCHEMBL26220887 | 0.75 | DNM1 (0.40) | SIGMAR1LMNACNR1ADRA1ATDP1 | |
| SCHEMBL24942548 | 0.75 | SIGMAR1 (0.33) | SIGMAR1LMNACNR1ADRA1ATDP1 | |
| SCHEMBL2489804 | 0.75 | LMNA (0.54) | SIGMAR1LMNACNR1ADRA1ATDP1 | |
| SCHEMBL2484741 | 0.75 | LMNA (0.54) | SIGMAR1LMNACNR1ADRA1ATDP1 | |
| SCHEMBL22162261 | 0.75 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL383714 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215435-B1 | 2-OXA-ISOCEPHEM COMPOUNDS, COMPOSITIONS CONTAINING SAME AND PROCESSES FOR PREPARING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-4831026-A | ANTIBIOTICS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0215435-A1 | 2-Oxa-isocephem compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-03-25 | — | — | EP | disclosed |