Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4685958 | 0.91 | ALDH1A1 (0.49) | NPC1RAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL4686194 | 0.86 | RAB9A (0.48) | NPC1RAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL4325251 | 0.85 | ALDH1A1 (0.58) | NPC1RAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL10968197 | 0.79 | NUDT1 (0.41) | NPC1RAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL9039622 | 0.79 | ALDH1A1 (0.53) | NPC1RAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL11360935 | 0.77 | MEN1 (0.50) | NPC1RAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL9435490 | 0.77 | SMN1; SMN2 (0.57) | NPC1RAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL7812101 | 0.77 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL423622 | 0.77 | SMN1; SMN2 (0.57) | NPC1RAB9ASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL3749399 | 0.77 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232623-B1 | 1-CARBACEPHALOSPORIN ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4892942-A | 1-CARBA (DETHIA)CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1990-01-09 | — | — | US | disclosed |
| US-4791106-A | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1988-12-13 | — | — | US | disclosed |
| EP-0232623-A1 | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |