Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10828884 | 0.89 | MAPT (0.54) | L3MBTL1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL10828876 | 0.89 | MAPT (0.54) | L3MBTL1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL9782455 | 0.88 | MAPT (0.56) | L3MBTL1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL9782447 | 0.88 | MAPT (0.56) | L3MBTL1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL9782611 | 0.84 | ITGA4 (0.43) | L3MBTL1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL8722807 | 0.84 | ITGA4 (0.43) | L3MBTL1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL6448822 | 0.83 | L3MBTL1 (0.53) | L3MBTL1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL6448813 | 0.83 | L3MBTL1 (0.53) | L3MBTL1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL27519961 | 0.83 | L3MBTL1 (0.53) | L3MBTL1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL7775216 | 0.82 | ALDH1A1 (0.55) | L3MBTL1KMT2APOLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236927-A | Reduced toxicity; side effect reduction | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1993-08-17 | — | — | US | disclosed |
| EP-0204529-B1 | ANTI-CANCER QUINAZOLINE DERIVATIVES | BTG INTERNATIONAL LIMITED (GB) | 1993-03-31 | — | — | EP | disclosed |
| EP-0204529-A2 | Anti-cancer quinazoline derivatives | BTG INTERNATIONAL LIMITED (GB) | 1986-12-10 | — | — | EP | disclosed |