Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9782611 | 1.00 | ITGA4 (0.43) | ITGA4ITGB7ALDH1A1MAPTADRB2 | |
| SCHEMBL9601134 | 0.84 | L3MBTL1 (0.49) | ALDH1A1MAPTL3MBTL1KMT2ALMNA | |
| SCHEMBL8721880 | 0.83 | ALOX5 (0.36) | MAPTGAATDP1 | |
| SCHEMBL9782470 | 0.83 | ALOX5 (0.36) | MAPTGAATDP1 | |
| SCHEMBL9228554 | 0.83 | ALOX5 (0.36) | MAPTGAATDP1 | |
| SCHEMBL17202877 | 0.83 | ITGA4 (0.61) | ITGA4ITGB7ALDH1A1MAPTPOLB | |
| SCHEMBL17202878 | 0.83 | ITGA4 (0.61) | ITGA4ITGB7ALDH1A1MAPTPOLB | |
| SCHEMBL6885928 | 0.82 | TYMS (0.37) | MAPTGAATDP1 | |
| SCHEMBL6885924 | 0.82 | TYMS (0.37) | MAPTGAATDP1 | |
| SCHEMBL6887180 | 0.80 | CLPP (0.43) | ALDH1A1MAPTGAAHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696270-B1 | 4-AMINO-FLUOROBENZAMIDES AND THEIR USE AS CYTOTOXIC PRODRUGS | CANCER RES CAMPAIGN TECH (GB) | 1998-11-04 | — | — | EP | disclosed |
| US-5019577-A | Novel compounds and use | BURROUGHS WELCOME CO. (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0341837-A2 | Glutamic acid derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1989-11-15 | — | — | EP | disclosed |