SCHEMBL9601916

SCHEMBL9601916

c1ccc2nc(-c3c4ccccc4nc4ccccc34)ccc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 9/20 0.53
NPC1 O15118 7/20 0.53
AR P10275 4/20 0.50
CYP3A4 P08684 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
ALDH1A1 P00352 7/20 0.47
HSD17B10 Q99714 5/20 0.47
HPGD P15428 5/20 0.47
KDM4E B2RXH2 5/20 0.47
SMN1; SMN2 Q16637 4/20 0.47
TP53 P04637 3/20 0.47
PKM P14618 3/20 0.47
MAPT P10636 3/20 0.47
ESR1 P03372 2/20 0.47
ESR2 Q92731 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30543754 1.00 RAB9A (0.53) RAB9ANPC1ARCYP3A4CYP1A2
SCHEMBL24662774 0.86 ESR1 (0.51) RAB9ANPC1ARCYP3A4CYP1A2
SCHEMBL12205159 0.84 RAB9A (0.59) RAB9ANPC1ARCYP3A4CYP1A2
SCHEMBL13045243 0.83 ALDH1A1 (0.45) RAB9ANPC1CYP3A4CYP1A2CYP2D6
SCHEMBL30873566 0.82 RAB9A (0.46) RAB9ANPC1ARCYP3A4CYP1A2
SCHEMBL14505862 0.82 AR (0.49) RAB9ANPC1ARCYP3A4CYP1A2
SCHEMBL9876096 0.82 AR (0.40) RAB9ANPC1ARCYP3A4CYP1A2
SCHEMBL18272727 0.81 AR (0.48) RAB9ANPC1ARCYP3A4CYP1A2
SCHEMBL4501372 0.81 KMT2A (0.45) RAB9ANPC1CYP3A4CYP1A2CYP2D6
SCHEMBL24662627 0.81 PTGS2 (0.48) RAB9ANPC1ARCYP3A4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0305545-B1 SUBSTITUTED ACRIDINE DERIVATIVES AND THEIR USE Hitachi Chemical Co., Ltd. (JP) 1993-02-10 EP claimed
CN-111315828-B Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2023-09-29 CN disclosed
CN-112154167-B Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2023-08-22 CN disclosed
CN-110114376-B Curable composition, method for producing cured product, cured product thereof, and adhesive using same 株式会社ADEKA 2022-06-14 CN disclosed
EP-3339331-B1 COMPOSITION ADEKA CORP (JP) 2022-02-16 EP disclosed
CN-108419438-B Coloring composition 株式会社艾迪科 2021-10-01 CN disclosed
CN-112154167-A Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2020-12-29 CN disclosed
CN-111566173-A Coating composition, method for curing the composition, barrier film, and method for producing cured product 株式会社艾迪科 2020-08-21 CN disclosed
WO-2020021969-A1 COMPOSITION, CURED PRODUCT, OPTICAL FILTER, AND PRODUCTION METHOD FOR CURED PRODUCT 株式会社ADEKA 2020-01-30 WO disclosed
CN-110114376-A Curable composition, method for producing cured product, cured product thereof, and adhesive using same 株式会社ADEKA 2019-08-09 CN disclosed
CN-108419438-A Coloured composition 株式会社艾迪科 2018-08-17 CN disclosed
EP-3339331-A1 COMPOSITION Adeka Corporation (JP) 2018-06-27 EP disclosed
CN-107636024-A Composition 株式会社艾迪科 2018-01-26 CN disclosed
EP-0305545-B1 SUBSTITUTED ACRIDINE DERIVATIVES AND THEIR USE Hitachi Chemical Co., Ltd. (JP) 1993-02-10 EP disclosed
US-5045433-A Photopolymerization initiators HITACHI CHEMICAL CO., LTD. (JP) 1991-09-03 US disclosed
EP-0305545-A1 SUBSTITUTED ACRIDINE DERIVATIVES AND THEIR USE Hitachi Chemical Co., Ltd. (JP) 1989-03-08 EP disclosed