SCHEMBL9876096

SCHEMBL9876096

Sc1ncc[nH]1.c1ccc2nc(-c3c4ccccc4nc4ccccc34)ccc2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 13/20 0.40
RAB9A P51151 5/20 0.40
NPC1 O15118 4/20 0.40
KDM4E B2RXH2 3/20 0.40
ALDH1A1 P00352 3/20 0.40
ALOX15 P16050 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
TP53 P04637 1/20 0.40
PKM P14618 1/20 0.40
HPGD P15428 1/20 0.40
TSHR P16473 1/20 0.40
HSD17B10 Q99714 1/20 0.40
CYP1A2 P05177 3/20 0.40
CYP3A4 P08684 3/20 0.40
CYP2D6 P10635 3/20 0.40
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
NISCH Q9Y2I1 1/20 0.38
LMNA P02545 2/20 0.38
PMP22 Q01453 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9876002 0.86 LMNA (0.44) RAB9ANPC1KDM4EALDH1A1ALOX15
SCHEMBL9875902 0.82 ESR1 (0.49) KDM4EALDH1A1SMN1; SMN2HPGDTSHR
SCHEMBL9601916 0.82 RAB9A (0.53) ARRAB9ANPC1KDM4EALDH1A1
SCHEMBL30543754 0.82 RAB9A (0.53) ARRAB9ANPC1KDM4EALDH1A1
SCHEMBL9875643 0.81 METAP2 (0.48) RAB9ANPC1KDM4EALDH1A1SMN1; SMN2
SCHEMBL9876007 0.79 ESR1 (0.42) ARRAB9ANPC1KDM4EALDH1A1
Phenazine SCHEMBL29069909 0.78 MAPT (0.46) RAB9ANPC1KDM4EALDH1A1SMN1; SMN2
SCHEMBL9875363 0.76 F2 (0.45) KDM4EALDH1A1ALOX15HPGDTSHR
Quinoline SCHEMBL28162881 0.76 ALDH1A1 (0.61) RAB9ANPC1KDM4EALDH1A1SMN1; SMN2
SCHEMBL24662774 0.71 ESR1 (0.51) ARRAB9ANPC1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5045433-A Photopolymerization initiators HITACHI CHEMICAL CO., LTD. (JP) 1991-09-03 US disclosed