Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.64 |
| ▸ | MMP1 | P03956 | 2/20 | 0.64 |
| ▸ | MMP9 | P14780 | 2/20 | 0.64 |
| ▸ | MMP13 | P45452 | 2/20 | 0.64 |
| ▸ | MMP3 | P08254 | 1/20 | 0.64 |
| ▸ | MMP7 | P09237 | 1/20 | 0.64 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | CA1 | P00915 | 4/20 | 0.57 |
| ▸ | CA2 | P00918 | 4/20 | 0.57 |
| ▸ | MMP8 | P22894 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
| ▸ | HPN | P05981 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7062840 | 1.00 | MMP2 (0.64) | MMP2MMP1MMP9MMP13MMP3 | |
| SCHEMBL15251688 | 1.00 | MMP2 (0.64) | MMP2MMP1MMP9MMP13MMP3 | |
| SCHEMBL7668182 | 0.85 | MMP9 (0.72) | MMP2MMP1MMP9MMP13MMP3 | |
| SCHEMBL7673418 | 0.85 | MMP9 (0.72) | MMP2MMP1MMP9MMP13MMP3 | |
| SCHEMBL7066619 | 0.83 | MMP9 (0.71) | MMP2MMP1MMP9MMP13MMP3 | |
| SCHEMBL3969625 | 0.83 | MMP9 (0.71) | MMP2MMP1MMP9MMP13MMP3 | |
| SCHEMBL11351046 | 0.83 | MMP9 (0.71) | MMP2MMP1MMP9MMP13MMP3 | |
| SCHEMBL7667679 | 0.83 | MMP9 (0.72) | MMP2MMP1MMP9MMP13MMP3 | |
| SCHEMBL7676199 | 0.83 | MMP9 (0.72) | MMP2MMP1MMP9MMP13MMP3 | |
| SCHEMBL5191083 | 0.83 | MMP2 (0.70) | MMP2MMP1MMP9MMP13MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993015047-A1 | AMINO ACID DERIVATIVES AS PAF ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-08-05 | — | — | WO | disclosed |