Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DDX3X | O00571 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6006960 | 0.75 | MAPT (0.44) | MAPTTSHRDDX3XHCAR2HCAR3 | |
| SCHEMBL6006605 | 0.74 | LMNA (0.44) | MAPTTSHRDDX3XALDH1A1NPSR1 | |
| SCHEMBL6007018 | 0.72 | NPSR1 (0.44) | MAPTTSHRDDX3XALDH1A1NPSR1 | |
| SCHEMBL6004545 | 0.72 | NPSR1 (0.44) | MAPTTSHRDDX3XALDH1A1NPSR1 | |
| SCHEMBL6007172 | 0.71 | TSHR (0.39) | MAPTTSHRALDH1A1 | |
| SCHEMBL8811268 | 0.70 | GPR84 (0.36) | ALDH1A1 | |
| SCHEMBL6007023 | 0.69 | CTSK (0.33) | MAPTDDX3X | |
| SCHEMBL2574903 | 0.69 | KDM4E (0.44) | MAPTALDH1A1NPSR1 | |
| SCHEMBL6007194 | 0.68 | ALDH1A1 (0.42) | MAPTTSHRDDX3XHCAR2HCAR3 | |
| Benzene SCHEMBL27911231 | 0.68 | TLR8 (0.41) | MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5217985-A | RENAL-SELECTIVE BIPHENYLALKYL 1H-SUBSTITUTED-1,2,4-TRIAZOLE ANGIOTENSIN II ANTAGONISTS FOR TREATMENT OF HYPERTENSION | G. D. SEARLE & CO. (US) | 1993-06-08 | — | — | US | disclosed |