Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 2/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9603801 | 0.84 | SLC9A1 (0.44) | SLC9A1ATRKMOHPGDSCNR2 | |
| SCHEMBL7440169 | 0.78 | SLC9A1 (0.41) | SLC9A1JAK2JAK3KMOHPGDS | |
| SCHEMBL7438138 | 0.77 | HPGDS (0.54) | SLC9A1ATRJAK3KMOHPGDS | |
| SCHEMBL7440162 | 0.76 | SLC9A1 (0.41) | SLC9A1KMOHPGDSMAPTKDM4E | |
| SCHEMBL17518810 | 0.66 | IDO1 (0.49) | KMOMAPTKDM4EMEN1KMT2A | |
| SCHEMBL29212573 | 0.66 | IDO1 (0.51) | KMOHPGDSMAPTKDM4EMEN1 | |
| SCHEMBL30902079 | 0.66 | IDO1 (0.51) | KMOHPGDSMAPTKDM4EMEN1 | |
| SCHEMBL18329423 | 0.66 | TAAR1 (0.49) | KMOHPGDSMAPTKDM4EMEN1 | |
| SCHEMBL7434800 | 0.65 | SLC9A1 (0.41) | SLC9A1KMOMAPTPIN1 | |
| SCHEMBL14564384 | 0.64 | NR4A2 (0.49) | KMOMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254575-A | 4-aryl-thiazole derivatives | AKZO N.V. (NL) | 1993-10-19 | — | — | US | disclosed |