Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 3/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 2/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434800 | 0.87 | SLC9A1 (0.41) | SLC9A1MAPTKMOIDO1ICMT | |
| SCHEMBL7426997 | 0.87 | MAPT (0.36) | SLC9A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL7440591 | 0.81 | ALPL (0.35) | SLC9A1MAPTPTGS2ALDH1A1PKM | |
| SCHEMBL9603804 | 0.78 | SLC9A1 (0.42) | SLC9A1HPGDSMEN1KMT2AKDM4E | |
| SCHEMBL7433050 | 0.78 | SCN9A (0.43) | SLC9A1HPGDSMEN1KMT2AKDM4E | |
| SCHEMBL7438138 | 0.76 | HPGDS (0.54) | SLC9A1HPGDSMEN1KMT2AKDM4E | |
| SCHEMBL9603801 | 0.74 | SLC9A1 (0.44) | SLC9A1HPGDSMEN1KMT2AKDM4E | |
| SCHEMBL7440162 | 0.73 | SLC9A1 (0.41) | SLC9A1HPGDSMEN1KMT2AKDM4E | |
| SCHEMBL17518810 | 0.66 | IDO1 (0.49) | MEN1KMT2AKDM4EMAPTKMO | |
| SCHEMBL7438866 | 0.65 | SCN9A (0.41) | SLC9A1KDM4EKMOPTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506194-B1 | 4-aryl-thiazole or imidazole derivatives | AKZO NOBEL NV (NL) | 1996-08-21 | — | — | EP | disclosed |
| US-5462959-A | 4-aryl-imidazole derivatives | AKZO N.V. (NL) | 1995-10-31 | — | — | US | disclosed |
| EP-0506194-A1 | 4-aryl-thiazole or imidazole derivatives | Akzo Nobel N.V. (NL) | 1992-09-30 | — | — | EP | disclosed |