Sugi Predict

Sugi Predict / Compounds / SCHEMBL9603934

SCHEMBL9603934

SCHEMBL9603934

Cc1cc2nc(-c3ccc(-c4cccc5c4sc4ccccc45)cc3)oc2cc1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 1/20 0.46
▸ SMN1; SMN2 Q16637 9/20 0.43
▸ NPC1 O15118 9/20 0.43
▸ RAB9A P51151 9/20 0.43
▸ KDM4E B2RXH2 8/20 0.43
▸ MAPT P10636 8/20 0.43
▸ HSD17B10 Q99714 6/20 0.43
▸ ALDH1A1 P00352 5/20 0.43
▸ HPGD P15428 4/20 0.43
▸ KMT2A Q03164 1/20 0.42
▸ TP53 P04637 5/20 0.41
▸ GAA P10253 2/20 0.41
▸ CASP3 P42574 2/20 0.40
▸ SENP8 Q96LD8 2/20 0.40
▸ SENP7 Q9BQF6 2/20 0.40
▸ SENP6 Q9GZR1 2/20 0.40
▸ POLB P06746 1/20 0.40
▸ PRKDC P78527 2/20 0.40
▸ VSIR Q9H7M9 1/20 0.38
▸ TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9603950 0.88 ALOX5 (0.48) ALOX5SMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL9603938 0.88 NPC1 (0.52) ALOX5SMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL9603930 0.88 KDM4E (0.57) ALOX5SMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL8512669 0.84 NPC1 (0.50) ALOX5SMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL9603947 0.84 ALOX5 (0.46) ALOX5SMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL9603948 0.84 VSIR (0.47) ALOX5SMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL9603939 0.84 ALOX5 (0.45) ALOX5SMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL9603887 0.83 NPC1 (0.49) ALOX5SMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL9603931 0.83 ALOX5 (0.44) ALOX5NPC1MAPTALDH1A1KMT2A
SCHEMBL9603964 0.81 ALOX5 (0.43) ALOX5SMN1; SMN2NPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8546584-B2 Benzoxazole derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-10-01 — — US disclosed
US-8546584-B2 Benzoxazole derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-10-01 — — US disclosed
US-20120132896-A1 Benzoxazole Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD 2012-05-31 — — US disclosed
US-20120132896-A1 Benzoxazole Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD 2012-05-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120132896-A1 Benzoxazole Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device XDH, AOX1, CYP4X1 ALOX5 720/4885SMN1; SMN2 3345/4885NPC1 4611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.