Sugi Predict

Sugi Predict / Compounds / SCHEMBL9603974

SCHEMBL9603974

SCHEMBL9603974

CC1(C)c2cc(-c3nc4ccccc4o3)ccc2-c2ccc(-c3cccc4c3oc3ccccc34)cc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 2/20 0.47
▸ NPC1 O15118 8/20 0.44
▸ KDM4E B2RXH2 8/20 0.43
▸ ALDH1A1 P00352 6/20 0.43
▸ HPGD P15428 6/20 0.43
▸ RAB9A P51151 6/20 0.43
▸ SMN1; SMN2 Q16637 5/20 0.43
▸ MAPT P10636 3/20 0.43
▸ HSD17B10 Q99714 3/20 0.43
▸ USP2 O75604 2/20 0.43
▸ HCRTR1 O43613 2/20 0.43
▸ TSHR P16473 1/20 0.43
▸ MAPK1 P28482 1/20 0.43
▸ CASP3 P42574 1/20 0.43
▸ NPSR1 Q6W5P4 1/20 0.43
▸ SENP8 Q96LD8 1/20 0.43
▸ SENP7 Q9BQF6 1/20 0.43
▸ SENP6 Q9GZR1 1/20 0.43
▸ TP53 P04637 5/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9604037 0.89 ALOX5 (0.46) ALOX5NPC1KDM4EALDH1A1HPGD
SCHEMBL9603979 0.89 ALOX5 (0.47) ALOX5NPC1KDM4EALDH1A1HPGD
SCHEMBL9603975 0.87 ALOX5 (0.46) ALOX5NPC1KDM4EALDH1A1HPGD
SCHEMBL20276869 0.87 ALOX5 (0.59) ALOX5MEN1KMT2AATM
SCHEMBL8281466 0.86 ALOX5 (0.51) ALOX5NPC1KDM4EALDH1A1HPGD
SCHEMBL12324541 0.85 ALOX5 (0.57) ALOX5MEN1KMT2AATM
SCHEMBL9603968 0.85 ALOX5 (0.53) ALOX5NPC1KDM4EALDH1A1HPGD
SCHEMBL24570469 0.84 KDM4E (0.40) NPC1KDM4EALDH1A1HPGDRAB9A
SCHEMBL9603971 0.84 ALOX5 (0.53) ALOX5NPC1KDM4EALDH1A1HPGD
SCHEMBL9603978 0.84 ALOX5 (0.52) ALOX5NPC1KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8546584-B2 Benzoxazole derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-10-01 — — US disclosed
US-8546584-B2 Benzoxazole derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-10-01 — — US disclosed
US-20120132896-A1 Benzoxazole Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD 2012-05-31 — — US disclosed
US-20120132896-A1 Benzoxazole Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD 2012-05-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120132896-A1 Benzoxazole Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device XDH, AOX1, CYP4X1 ALOX5 720/4885NPC1 4611/4885KDM4E 2142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.