Sugi Predict

Sugi Predict / Compounds / SCHEMBL9604037

SCHEMBL9604037

SCHEMBL9604037

CC1(C)c2ccccc2-c2ccc(-c3cccc4nc(-c5ccc(-c6cccc7c6oc6ccccc67)cc5)oc34)cc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 2/20 0.46
▸ PRKDC P78527 1/20 0.38
▸ ESR1 P03372 1/20 0.37
▸ ESR2 Q92731 1/20 0.37
▸ GGPS1 O95749 1/20 0.36
▸ DHODH Q02127 1/20 0.36
▸ PDE4C Q08493 3/20 0.35
▸ NPC1 O15118 4/20 0.34
▸ KDM4E B2RXH2 2/20 0.34
▸ ALDH1A1 P00352 2/20 0.34
▸ HPGD P15428 2/20 0.34
▸ TP53 P04637 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ HSD17B10 Q99714 1/20 0.34
▸ RAB9A P51151 3/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ ATM Q13315 1/20 0.34
▸ JAK2 O60674 1/20 0.34
▸ JAK1 P23458 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9604040 0.89 ALOX5 (0.47) ALOX5PRKDCESR1ESR2GGPS1
SCHEMBL9603974 0.89 ALOX5 (0.47) ALOX5NPC1KDM4EALDH1A1HPGD
SCHEMBL12324541 0.88 ALOX5 (0.57) ALOX5PRKDCGGPS1MEN1KMT2A
SCHEMBL16017825 0.87 ALOX5 (0.56) ALOX5PRKDCGGPS1MEN1KMT2A
SCHEMBL8281444 0.86 ALOX5 (0.45) ALOX5PRKDCESR1GGPS1NPC1
SCHEMBL9604041 0.86 ALOX5 (0.44) ALOX5PRKDCESR1ESR2GGPS1
SCHEMBL20276869 0.85 ALOX5 (0.59) ALOX5PRKDCGGPS1MEN1KMT2A
SCHEMBL18086150 0.84 ALOX5 (0.53) ALOX5PRKDCGGPS1MEN1KMT2A
SCHEMBL12612626 0.83 ALOX5 (0.47) ALOX5PRKDCGGPS1MEN1KMT2A
SCHEMBL4549432 0.83 ALOX5 (0.44) ALOX5PRKDCGGPS1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8546584-B2 Benzoxazole derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-10-01 — — US disclosed
US-8546584-B2 Benzoxazole derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-10-01 — — US disclosed
US-20120132896-A1 Benzoxazole Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD 2012-05-31 — — US disclosed
US-20120132896-A1 Benzoxazole Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD 2012-05-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120132896-A1 Benzoxazole Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device XDH, AOX1, CYP4X1 ALOX5 720/4885PRKDC 4516/4885ESR1 99/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.