Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.46 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9604017 | 0.93 | MTNR1A (0.53) | MTNR1AMTNR1BESR2ESR1ALOX5 | |
| SCHEMBL9604015 | 0.91 | MTNR1A (0.46) | MTNR1AMTNR1BESR2ESR1ALOX5 | |
| SCHEMBL9604023 | 0.86 | MTNR1A (0.43) | MTNR1AMTNR1BESR2ALOX5TP53 | |
| SCHEMBL9604034 | 0.83 | ALOX5 (0.51) | ESR2ESR1ALOX5TP53SMN1; SMN2 | |
| SCHEMBL9604044 | 0.82 | NPC1 (0.52) | ESR2ESR1ALOX5TP53SMN1; SMN2 | |
| SCHEMBL9604018 | 0.82 | ALOX5 (0.48) | ESR2ESR1ALOX5TP53SMN1; SMN2 | |
| SCHEMBL9604035 | 0.82 | DHODH (0.53) | ESR2ESR1ALOX5TP53SMN1; SMN2 | |
| SCHEMBL9603967 | 0.81 | NPC1 (0.55) | ALOX5TP53SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL9604038 | 0.81 | ALOX5 (0.49) | ESR2ESR1ALOX5TP53SMN1; SMN2 | |
| SCHEMBL9603977 | 0.80 | NPC1 (0.54) | ALOX5TP53SMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8546584-B2 | Benzoxazole derivative, light-emitting element, light-emitting device, electronic device, and lighting device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2013-10-01 | — | — | US | disclosed |
| US-8546584-B2 | Benzoxazole derivative, light-emitting element, light-emitting device, electronic device, and lighting device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2013-10-01 | — | — | US | disclosed |
| US-20120132896-A1 | Benzoxazole Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD | 2012-05-31 | — | — | US | disclosed |
| US-20120132896-A1 | Benzoxazole Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120132896-A1 | Benzoxazole Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device | XDH, AOX1, CYP4X1 | MTNR1A 302/4885MTNR1B 935/4885ESR2 214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.