SCHEMBL9604019

SCHEMBL9604019

Cc1cccc2oc(-c3ccc(-c4cccc5c4oc4ccccc45)cc3)nc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.48
CEPT1 Q9Y6K0 1/20 0.45
TOP2A P11388 1/20 0.40
PTPN1 P18031 2/20 0.39
TP53 P04637 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 3/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
HSD17B10 Q99714 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
TSHR P16473 1/20 0.38
CYP2C19 P33261 1/20 0.38
PRKDC P78527 2/20 0.37
PIK3CD O00329 1/20 0.37
PIK3CB P42338 1/20 0.37
AGPAT2 O15120 1/20 0.37
GGPS1 O95749 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9604013 0.89 ALOX5 (0.47) ALOX5CEPT1TOP2ATP53RXFP1
SCHEMBL9604028 0.87 ALOX5 (0.50) ALOX5TOP2ATP53ALDH1A1KDM4E
SCHEMBL9604018 0.85 ALOX5 (0.48) ALOX5CEPT1PTPN1TP53ALDH1A1
SCHEMBL9604021 0.84 ALOX5 (0.47) ALOX5TOP2APTPN1ALDH1A1KDM4E
SCHEMBL9604022 0.82 ALOX5 (0.49) ALOX5TP53ALDH1A1KDM4EKMT2A
SCHEMBL16231622 0.82 CEPT1 (0.54) CEPT1TOP2APTPN1TP53ALDH1A1
SCHEMBL9603967 0.81 NPC1 (0.55) ALOX5TP53ALDH1A1KDM4EMEN1
SCHEMBL20714156 0.81 ALOX5 (0.50) ALOX5TOP2APTPN1TP53ALDH1A1
SCHEMBL9604029 0.81 ALOX5 (0.49) ALOX5TOP2AALDH1A1KDM4EMEN1
SCHEMBL9603977 0.80 NPC1 (0.54) ALOX5TP53ALDH1A1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8546584-B2 Benzoxazole derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-10-01 US disclosed
US-8546584-B2 Benzoxazole derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-10-01 US disclosed
US-20120132896-A1 Benzoxazole Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD 2012-05-31 US disclosed
US-20120132896-A1 Benzoxazole Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD 2012-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120132896-A1 Benzoxazole Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device XDH, AOX1, CYP4X1 ALOX5 720/4885CEPT1 3656/4885TOP2A 3581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.