SCHEMBL960188

SCHEMBL960188

CNCCCC(=O)NN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL960835 0.85
SCHEMBL2742896 0.80
SCHEMBL218953 0.79 KDM4E (0.60)
SCHEMBL28219205 0.79 ALDH1A1 (0.62)
SCHEMBL49856 0.79 ALDH1A1 (0.62)
Hydrochloric Acid SCHEMBL2022572 0.78 LMNA (0.46)
SCHEMBL10047432 0.78 CTSD (0.54)
SCHEMBL13492302 0.78 CTSD (0.54)
SCHEMBL15597179 0.77 CNR1 (0.51)
SCHEMBL962265 0.77 CTSD (0.60)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021220185-A1 AZALACTAM COMPOUNDS AS HPK1 INHIBITORS PFIZER INC. (US) 2021-11-04 WO disclosed
WO-2015150890-A1 A PROCESS FOR PREPARATION OF TRANS-SULFURIC ACID MONO-{2-(5-(3-AMINO-PROPYL)-[1,3,4]OXADIAZOL-2-YL]-7-OXO-1,6-DIAZABICYCLO [3.2.1] OCT-6-YL}ESTER WOCKHARDT LIMITED (IN) 2015-10-08 WO disclosed
EP-2248833-B1 MODIFIED DIENE RUBBER, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION USING THE SAME, AND TIRE BRIDGESTONE CORP (JP) 2014-03-26 EP disclosed
US-20130289165-A1 COMPOSITION BASED ON NATURAL RUBBER AND CARBON BLACK COMPRISING A HYDRAZIDE, A HYDRAZONE AND A POLYAMINE MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2013-10-31 US disclosed
EP-2655495-A1 COMPOSITION BASED ON NATURAL RUBBER AND CARBON BLACK COMPRISING A HYDRAZIDE, A HYDRAZONE AND A POLYAMINE Compagnie Générale des Etablissements Michelin (FR) 2013-10-30 EP disclosed
US-8389641-B2 Modified diene rubber, production method thereof, and rubber composition and tire using the rubber BRIDGESTONE CORPORATION (JP) 2013-03-05 US disclosed
WO-2012084821-A1 COMPOSITION BASED ON NATURAL RUBBER AND CARBON BLACK COMPRISING A HYDRAZIDE, A HYDRAZONE AND A POLYAMINE COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2012-06-28 WO disclosed
US-20110003911-A1 MODIFIED DIENE RUBBER, PRODUCTION METHOD THEREOF, AND RUBBER COMPOSITION AND TIRE USING THE RUBBER BRIDGESTONE CORPORATION (JP) 2011-01-06 US disclosed
EP-2248833-A1 MODIFIED DIENE RUBBER, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION USING THE SAME, AND TIRE Bridgestone Corporation (JP) 2010-11-10 EP disclosed
US-20100249336-A1 MODIFIED NATURAL RUBBER AND METHOD FOR PRODUCING SAME, AND RUBBER COMPOSITION AND TIRE USING SUCH A MODIFIED NATURAL RUBBER BRIDGESTONE CORPORATION (JP) 2010-09-30 US disclosed
EP-2206730-A1 MODIFIED NATURAL RUBBER, PROCESS FOR PRODUCTION OF THE SAME, AND RUBBER COMPOSITION AND TIRE EACH COMPRISING THE SAME Bridgestone Corporation (JP) 2010-07-14 EP disclosed