Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1088806 | 0.82 | CTSK (0.35) | CTSKDGAT1 | |
| SCHEMBL3977407 | 0.80 | CTSK (0.34) | CTSKDGAT1 | |
| SCHEMBL9746433 | 0.80 | CTSK (0.34) | CTSKDGAT1 | |
| SCHEMBL1414348 | 0.80 | DGAT1 (0.40) | CTSKTDP1DGAT1 | |
| SCHEMBL1089166 | 0.78 | SPHK1 (0.35) | CTSKDGAT1 | |
| SCHEMBL15418773 | 0.78 | TDP1 (0.43) | CTSKTDP1 | |
| SCHEMBL9604817 | 0.77 | CTSK (0.33) | CTSK | |
| SCHEMBL27546342 | 0.77 | CTSK (0.33) | CTSK | |
| SCHEMBL16885807 | 0.75 | DGAT1 (0.37) | CTSKTDP1DGAT1 | |
| SCHEMBL1088319 | 0.75 | SPHK1 (0.42) | CTSKTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018087-A1 | SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS | NVISION IMAGING TECHNOLOGIES GMBH (DE) | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018087-A1 | SYSTEMS AND METHODS FOR GENERATION OF HYPERPOLARIZED MATERIALS | GLS2, HNMT, FH | CTSK 4139/4885TDP1 2271/4885DGAT1 3122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.