Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 18/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31193486 | 0.85 | PDK2 (0.56) | PDK2GSTO1 | |
| SCHEMBL95711 | 0.85 | PDK2 (0.56) | PDK2GSTO1 | |
| SCHEMBL22295266 | 0.81 | PDK2 (0.37) | PDK2TDP1GSTO1 | |
| SCHEMBL96053 | 0.74 | MAPT (0.49) | PDK2TDP1 | |
| SCHEMBL4762110 | 0.72 | KCNA3 (0.52) | TDP1 | |
| SCHEMBL7536898 | 0.72 | KCNA3 (0.52) | TDP1 | |
| SCHEMBL5999278 | 0.72 | PDK2 (0.38) | PDK2TDP1GSTO1 | |
| SCHEMBL18837357 | 0.72 | NPC1 (0.55) | TDP1GSTO1 | |
| SCHEMBL7777147 | 0.72 | PDK2 (0.41) | PDK2TDP1GSTO1 | |
| SCHEMBL13502291 | 0.71 | TDP1 (0.41) | PDK2TDP1GSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2612845-B1 | AROMATIC COMPOUND CONTAINING SPECIFIC BRANCH | AJINOMOTO KK (JP) | 2020-08-05 | — | — | EP | disclosed |
| EP-2612845-B1 | AROMATIC COMPOUND CONTAINING SPECIFIC BRANCH | AJINOMOTO KK (JP) | 2020-08-05 | — | — | EP | disclosed |
| US-10711033-B2 | Branched chain-containing aromatic compound | AJINOMOTO CO., INC. (JP) | 2020-07-14 | — | — | US | disclosed |
| US-20170008922-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | AJINOMOTO CO., INC. (JP) | 2017-01-12 | — | — | US | disclosed |
| US-20170008922-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | AJINOMOTO CO., INC. (JP) | 2017-01-12 | — | — | US | disclosed |
| US-20170008922-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | AJINOMOTO CO., INC. (JP) | 2017-01-12 | — | — | US | disclosed |
| US-9499579-B2 | Branched chain-containing aromatic compound | AJINOMOTO CO., INC. (JP) | 2016-11-22 | — | — | US | disclosed |
| US-9499579-B2 | Branched chain-containing aromatic compound | AJINOMOTO CO., INC. (JP) | 2016-11-22 | — | — | US | disclosed |
| US-9499579-B2 | Branched chain-containing aromatic compound | AJINOMOTO CO., INC. (JP) | 2016-11-22 | — | — | US | disclosed |
| US-20140005359-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | AJINOMOTO CO., INC. (JP) | 2014-01-02 | — | — | US | disclosed |
| US-8546534-B2 | Branched chain-containing aromatic compound | AJINOMOTO CO., INC. (JP) | 2013-10-01 | — | — | US | disclosed |
| US-8546534-B2 | Branched chain-containing aromatic compound | AJINOMOTO CO., INC. (JP) | 2013-10-01 | — | — | US | disclosed |
| US-8546534-B2 | Branched chain-containing aromatic compound | AJINOMOTO CO., INC. (JP) | 2013-10-01 | — | — | US | disclosed |
| EP-2612845-A1 | AROMATIC COMPOUND CONTAINING SPECIFIC BRANCH | Ajinomoto Co., Inc. (JP) | 2013-07-10 | — | — | EP | disclosed |
| US-20120059149-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | AJINOMOTO CO. INC. (JP) | 2012-03-08 | — | — | US | disclosed |
| US-20120059149-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | AJINOMOTO CO. INC. (JP) | 2012-03-08 | — | — | US | disclosed |
| US-20120059149-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | AJINOMOTO CO. INC. (JP) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059149-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | VIP, BCAT2, IAPP | PDK2 758/4885TDP1 4323/4885GSTO1 4855/4885 |
| US-10711033-B2 | Branched chain-containing aromatic compound | VIP, IAPP, BCAT1 | PDK2 1569/4885TDP1 4224/4885GSTO1 4884/4885 |
| US-20170008922-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | VIP, IAPP, BCAT1 | PDK2 1569/4885TDP1 4224/4885GSTO1 4884/4885 |
| US-20140005359-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | VIP, IAPP, BCAT1 | PDK2 1569/4885TDP1 4224/4885GSTO1 4884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.