Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14288507 | 0.80 | MAPT (0.72) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL18837357 | 0.79 | NPC1 (0.55) | MAPTNPC1ALDH1A1RAB9ATDP1 | |
| SCHEMBL18015983 | 0.78 | MAPT (0.69) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL13502291 | 0.78 | TDP1 (0.41) | MAPTKMT2ATDP1PDK2ALOX5 | |
| SCHEMBL6857008 | 0.78 | TDP1 (0.58) | MAPTKMT2AGAATDP1ALOX5 | |
| SCHEMBL16340342 | 0.78 | TDP1 (0.58) | MAPTKMT2AGAATDP1ALOX5 | |
| SCHEMBL7536898 | 0.77 | KCNA3 (0.52) | TDP1ALOX5 | |
| SCHEMBL4762110 | 0.77 | KCNA3 (0.52) | TDP1ALOX5 | |
| SCHEMBL538615 | 0.76 | MAPT (0.67) | MAPTKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL13502293 | 0.76 | TDP1 (0.45) | NPC1RAB9ATDP1PDK2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2612845-B1 | AROMATIC COMPOUND CONTAINING SPECIFIC BRANCH | AJINOMOTO KK (JP) | 2020-08-05 | — | — | EP | disclosed |
| US-10711033-B2 | Branched chain-containing aromatic compound | AJINOMOTO CO., INC. (JP) | 2020-07-14 | — | — | US | disclosed |
| US-10711033-B2 | Branched chain-containing aromatic compound | AJINOMOTO CO., INC. (JP) | 2020-07-14 | — | — | US | disclosed |
| US-20170008922-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | AJINOMOTO CO., INC. (JP) | 2017-01-12 | — | — | US | disclosed |
| US-20170008922-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | AJINOMOTO CO., INC. (JP) | 2017-01-12 | — | — | US | disclosed |
| US-20170008922-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | AJINOMOTO CO., INC. (JP) | 2017-01-12 | — | — | US | disclosed |
| US-9499579-B2 | Branched chain-containing aromatic compound | AJINOMOTO CO., INC. (JP) | 2016-11-22 | — | — | US | disclosed |
| US-9499579-B2 | Branched chain-containing aromatic compound | AJINOMOTO CO., INC. (JP) | 2016-11-22 | — | — | US | disclosed |
| US-9499579-B2 | Branched chain-containing aromatic compound | AJINOMOTO CO., INC. (JP) | 2016-11-22 | — | — | US | disclosed |
| US-20140005359-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | AJINOMOTO CO., INC. (JP) | 2014-01-02 | — | — | US | disclosed |
| US-8546534-B2 | Branched chain-containing aromatic compound | AJINOMOTO CO., INC. (JP) | 2013-10-01 | — | — | US | disclosed |
| US-8546534-B2 | Branched chain-containing aromatic compound | AJINOMOTO CO., INC. (JP) | 2013-10-01 | — | — | US | disclosed |
| US-8546534-B2 | Branched chain-containing aromatic compound | AJINOMOTO CO., INC. (JP) | 2013-10-01 | — | — | US | disclosed |
| EP-2612845-A1 | AROMATIC COMPOUND CONTAINING SPECIFIC BRANCH | Ajinomoto Co., Inc. (JP) | 2013-07-10 | — | — | EP | disclosed |
| EP-2612845-A1 | AROMATIC COMPOUND CONTAINING SPECIFIC BRANCH | Ajinomoto Co., Inc. (JP) | 2013-07-10 | — | — | EP | disclosed |
| US-20120059149-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | AJINOMOTO CO. INC. (JP) | 2012-03-08 | — | — | US | disclosed |
| US-20120059149-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | AJINOMOTO CO. INC. (JP) | 2012-03-08 | — | — | US | disclosed |
| US-20120059149-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | AJINOMOTO CO. INC. (JP) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059149-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | VIP, BCAT2, IAPP | MAPT 892/4885KMT2A 4605/4885MEN1 2743/4885 |
| US-10711033-B2 | Branched chain-containing aromatic compound | VIP, IAPP, BCAT1 | MAPT 715/4885KMT2A 4327/4885MEN1 2297/4885 |
| US-20170008922-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | VIP, IAPP, BCAT1 | MAPT 715/4885KMT2A 4327/4885MEN1 2297/4885 |
| US-20140005359-A1 | BRANCHED CHAIN-CONTAINING AROMATIC COMPOUND | VIP, IAPP, BCAT1 | MAPT 715/4885KMT2A 4327/4885MEN1 2297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.