Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CASR | P41180 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16545816 | 0.86 | CASR (0.51) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL3976660 | 0.82 | ADRB2 (0.44) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL16280900 | 0.81 | KDM4E (0.42) | KMT2AKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL17617030 | 0.78 | ALDH1A1 (0.53) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL17831499 | 0.78 | MEN1 (0.52) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL9606976 | 0.77 | KDM4E (0.38) | KMT2AKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL16280855 | 0.77 | KDM4E (0.38) | KMT2AKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9606985 | 0.77 | KDM4E (0.38) | KMT2AKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL13415765 | 0.75 | LTA4H (0.49) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL20226244 | 0.75 | SMN1; SMN2 (0.44) | MEN1KMT2AKDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170074449-A1 | MODIFIED HYBRID SILICA AEROGELS | MIDCAP FUNDING IV TRUST | 2017-03-16 | — | — | US | disclosed |
| US-8906973-B2 | Modified hybrid silica aerogels | ASPEN AEROGELS, INC. (US) | 2014-12-09 | — | — | US | disclosed |
| US-20120136079-A1 | MODIFIED HYBRID SILICA AEROGELS | ASPEN AEROGELS, INC. (US) | 2012-05-31 | — | — | US | disclosed |