Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.44 |
| ▸ | MAOB | P27338 | 7/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 2/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18003158 | 0.87 | MAOA (0.48) | MAOAMAOBMRGPRX4NPC1RAB9A | |
| SCHEMBL16399586 | 0.86 | BCHE (0.43) | MAOAMAOBMRGPRX4NPC1RAB9A | |
| SCHEMBL38652385 | 0.85 | RAB9A (0.46) | RAB9ASLC6A4PIM1DAOGPR84 | |
| SCHEMBL9607433 | 0.84 | ALDH1A1 (0.49) | RAB9ASLC6A4PIM1DAOGPR84 | |
| SCHEMBL6852425 | 0.80 | ALDH1A1 (0.52) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL8024555 | 0.80 | NPC1 (0.66) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL20546776 | 0.80 | SRD5A2 (0.44) | MAOAMAOBDAO | |
| SCHEMBL30644996 | 0.80 | SRD5A2 (0.44) | MAOAMAOBDAO | |
| SCHEMBL18002711 | 0.79 | GRIN2B (0.44) | SLC6A4GPR84 | |
| SCHEMBL18002003 | 0.79 | GRIN2B (0.45) | SLC6A4PIM1DAOGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |